Deletion of the gene for the African swine fever virus BCL-2 family member A179L increases virus uptake and apoptosis, but decreases virus spread in macrophages and reduces virulence in pigs
A. L. Reis, A. Rathakrishnan, L. V. Goulding, L. C. Goatley, C. Barber, L. K. Dixon
This study deletes the A179L gene from African swine fever virus, showing increased apoptosis and reduced virulence in pigs but decreased virus spread in macrophages.
bioRxiv · Apr 27, 2023Microbiology