Deconvolution of substrate processing by the 26S proteasome reveals a selective kinetic gateway to degradation
J. A. Bard, C. Bashore, K. C. Dong, A. Martin
The paper uses FRET and anisotropy assays to study proteasome kinetics and reveals a kinetic proofreading mechanism for substrate degradation.
bioRxiv · Jun 30, 2018Biochemistry