A. Martin

Neural activation down to the spinal cord during action language? A transcranial magnetic stimulation and peripheral nerve stimulation study.

This study investigates whether action language modulates spinal motor pathways, finding no effect on high-threshold motoneurons during action reading, unlike motor imagery.

Stress tolerance of multiple Salmonella enterica strains associated with foodborne outbreaks

This study evaluates stress tolerance in Salmonella enterica strains from foodborne outbreaks and non-outbreaks, finding enhanced tolerance to sanitizers and heat in many isolates.

CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti-tumoral compounds

This study uses CRISPR to eliminate the FOXL2 c.402C>G mutation in granulosa tumor cells, reducing malignancy and identifying anti-tumoral compounds.

Nub1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome

This paper identifies how Nub1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome through a novel mechanism involving structural dynamics and proteasomal engagement.

Development of BODIPY-based fluorescent probes for highly selective amino acid identification

This paper develops BODIPY-based fluorescent probes for selective amino acid identification through optimized spectral and photophysical properties.

Effect of 10 days of unilateral lower limb suspension on knee extensors neuromuscular function and spinal excitability

This study examines the effects of 10 days of unilateral lower limb suspension on knee extensors strength and spinal excitability, finding reduced strength and increased spinal reflexes.

Mean exercise torque is a critical factor influencing neuromuscular fatigability induced by exhausting contractions

This study examines how mean exercise torque affects neuromuscular fatigability during exhausting contractions, finding that torque loss during maximal voluntary contraction decreases after recovery regardless of contraction pattern.

A long non-coding RNA at the cortex locus controls adaptive colouration in butterflies

This study identifies a long non-coding RNA, ivory, at the cortex locus that controls adaptive colouration in butterflies by modulating pigmentation patterns through CRISPR mutagenesis.

Chikungunya virus infection disrupts lymph node lymphatic endothelial cell composition and function via MARCO

This study shows CHIKV infection disrupts lymph node lymphatic endothelial cell composition and function through MARCO interactions, leading to impaired antigen acquisition and increased inflammation.

EGFR-dependent actomyosin patterning coordinates morphogenetic movements between tissues

Substrate-interacting pore loops of two ATPase subunits determine the degradation efficiency of the 26S proteasome

This study investigates how pore-1 loops of ATPase subunits in the 26S proteasome affect substrate degradation efficiency using biochemical and single-molecule assays with yeast proteasomes.

Exposure to aldehyde cherry e-liquid flavouring and its vape by-product disrupts pulmonary surfactant biophysical function

This study shows that benzaldehyde and its by-product, benzaldehyde propylene glycol acetal, disrupt pulmonary surfactant biophysical function by interacting with surfactant proteins SP-B and SP-C.

The Pex6 N1 domain is required for Pex15 binding and proper assembly with Pex1

This study identifies the Pex6 N1 domain's role in binding Pex15 and stabilizing the Pex1/Pex6 heterohexamer, essential for peroxisome function.

Human Th17- and IgG3-associated autoimmunity induced by a translocating gut pathobiont

This study shows that the gut pathobiont Enterococcus gallinarum induces human Th17 and IgG3 autoantibody responses linked to disease activity in autoimmune patients.

Parasite-Induced IFN-g Regulates Host Defense via CD115 and mTOR-Dependent Mechanism of Tissue-Resident Macrophage Death

This study shows that IFN-gamma induces CD115 and mTOR-dependent death of tissue-resident macrophages, enhancing host resistance to Toxoplasma gondii.

Natural genetic variation underlying the negative effect of elevated CO2 on ionome composition in Arabidopsis thaliana

This study identifies genetic factors influencing the negative effect of elevated CO2 on ionome composition in Arabidopsis thaliana using genome-wide association mapping.

ENDO-LYSOSOME-TARGETED NANOPARTICLE DELIVERY OF ANTIVIRAL THERAPY FOR CORONAVIRUS INFECTIONS

This study develops lysosome-targeted nanoparticles loaded with mefloquine to inhibit coronavirus infection, showing effectiveness against SARS-CoV-2 and its variants in cell models.

Adaptive therapy for ovarian cancer: An integrated approach to PARP inhibitor scheduling

This study develops an adaptive therapy protocol for PARP inhibitors by combining mathematical modeling and experiments to optimize treatment scheduling and mitigate resistance.

A general strategy to develop fluorogenic polymethine dyes for bioimaging

This paper introduces a general strategy to create fluorogenic polymethine dyes for bioimaging, achieving red-shifted emissions and compatibility with multicolor imaging.

Targeted chromosomal barcoding establishes direct genotype-phenotype associations for antibiotic resistance in Mycobacterium abscessus

Signaling pathways involved in the repression of root nitrate uptake by nitrate in Arabidopsis thaliana

The paper identifies molecular elements and signaling pathways involved in the repression of NRT2 transporters and root nitrate uptake in Arabidopsis in response to nitrate.

Evolutionary dynamics of genome size and content during the adaptive radiation of Heliconiini butterflies

This study generates and analyzes 63 Heliconiini butterfly genomes to explore evolutionary patterns and genomic basis of traits during adaptive radiation.

The Nucleocapsid Protein Of SARS-CoV-2, Combined With ODN-39M, Is A Potential Component For An Intranasal Bivalent Pancorona Vaccine

This paper evaluates a bivalent intranasal vaccine candidate combining SARS-CoV-2 N protein and ODN-39M, showing cross-reactive immunity against SARS-CoV-1 and enhanced Th1 response when combined with RBD.

Genotypic sex shapes maternal care in the African Pygmy mouse, Mus minutoides

The paper shows that genotypic sex, not just gonadal hormones, influences maternal care in African pygmy mice, revealing a third female genotype with distinct care strategies and neural impacts.

Temporal integration of rod signals in luminance and chromatic pathways

The paper investigates how rod signals influence reaction times in luminance and chromatic pathways using a four-primary display.

Meta-analysis of the genetic loci of pigment pattern evolution in vertebrates

This study meta-analyzes genetic loci associated with vertebrate pigmentation patterns, finding that cis-regulatory mutations are more common in species with diverse pigment cell classes and certain trait types.

Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism

This study identifies steroid hormone catabolites as specific activators of the pyrin inflammasome through a non-canonical mechanism, linking them to autoinflammation and explaining steroid fever.

Ubiquitin modulates 26S proteasome conformational dynamics and promotes substrate degradation

This study uses single-molecule FRET to show ubiquitin chains regulate proteasome conformational dynamics, enhancing substrate degradation by stabilizing engagement-competent states.

Species hybridisation and clonal expansion as a new fungicide resistance evolutionary mechanism in Pyrenophora teres spp.

The paper identifies a natural hybrid of Ptt and Ptm fungi with azole resistance, showing recombination and clonal expansion contributing to fungicide resistance in barley.

Discovery of genes that modulate flavivirus replication in an interferon-dependent manner

The paper identifies twenty-one host genes that modulate flavivirus replication in an interferon-dependent manner using siRNA screening in ZIKV-infected microglial cells.