Lowering levels of reelin in entorhinal cortex layer II-neurons results in lowered levels of intracellular amyloid-β.
A. Kobro-Flatmoen, C. Battistin, R. N. Raveendran, C. Bjorkli, B. Skender, C. Kentros, G. K. Gouras, M. P. Witter
This study shows that lowering reelin in entorhinal cortex layer II neurons reduces intracellular amyloid-β levels without affecting human APP levels.
bioRxiv · Jan 28, 2022Pathology