Spatial patterning and immunosuppression of glioblastoma immune contexture in hypoxic niches
A. Sattiraju, S. Kang, Z. Chen, V. Marallano, C. Brusco, A. Ramakrishnan, L. Shen, D. Hambardzumyan, R. Friedel, H. Zou
This study identifies hypoxia-driven immunosuppression in glioblastoma by tracking TAM dynamics and reveals niche factors that promote immunotolerant states and poor prognosis.
bioRxiv · Mar 1, 2022Cancer Biology