3D Brain Vascular Niche Model Captures Invasive Behavior and Gene Signatures of Glioblastoma
V. K. Lee, R. Tejero, N. Silvia, A. Sattiraju, A. Ramakrishnan, L. Shen, A. Wojcinski, S. Kesari, R. H. Friedel, H. Zou, G. Dai
This paper develops a 3D brain vascular niche model to study GBM invasion and gene signatures, revealing glia-vascular contact influences transcriptional adaptation and poor prognosis.
bioRxiv · Jul 9, 2024Bioengineering