Glycan-induced protein dynamics in human norovirus P dimers depend on virus strain and deamidation status
J. Duelfer, H. Yan, M. N. Brodmerkel, R. Creutznacher, A. Mallagaray, T. Peters, C. Caleman, E. G. Marklund, C. Uetrecht
This study uses HDX-MS to analyze glycan-induced structural dynamics in norovirus P dimers across strains and deamidation states, revealing strain- and deamidation-dependent changes in protein flexibility and solvent exposure.
bioRxiv · Oct 7, 2020Biophysics