In-depth Analysis of the Sirtuin 5-regulated Mouse Brain Acylome using Library-free Data-Independent Acquisitions
J. Bons, J. Rose, R. Zhang, J. B. Burton, C. Carrico, E. Verdin, B. Schilling
This study presents a DIA-based workflow to analyze PTMs in mouse brains, identifying SIRT5-regulated malonylation and succinylation sites and their impact on metabolic and neurodegenerative pathways.
bioRxiv · Aug 6, 2022 · PreprintCell Biology