A. Cruz

Discovery of E6AP AZUL binding to UBQLN1/2 in cells, phase-separated droplets, and an AlphaFold-NMR integrated structure

The paper identifies E6AP AZUL binding to UBQLN1/2 UBA domains, shows phase separation, and presents an integrated AlphaFold-NMR structure.

Coenzyme A binding sites induce proximal acylation across protein families

The paper identifies that CoA-binding sites promote proximal lysine acylation in mitochondria through computational analysis and experimental validation.

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein

This study identifies SIRT5 as a proviral factor that interacts with SARS-CoV-2 Nsp14, enhancing viral replication and suggesting it as a therapeutic target.

FOXO1 promotes HIV Latency by suppressing ER stress in T cells

This study shows FOXO1 promotes HIV latency by suppressing ER stress in T cells and identifies pathways to selectively reverse quiescence and reduce viral reservoirs.

Cross-Infectivity of Vorticella across Genera of Mosquitoes for Development of Biological Mosquito Control Strategies

This study investigates the cross-infectivity of Vorticella protozoans across mosquito genera to develop biological control strategies for mosquitoes.

Freezing displayed by others is a learned cue of danger resulting from co-experiencing own-freezing and shock

This study shows that freezing displayed by others becomes a learned danger cue through auto-conditioning, where prior shock experience links self-freezing to threat.

Non-genetic intra-tumor heterogeneity is a major predictor of phenotypic heterogeneity and ongoing evolutionary dynamics in lung tumors

The paper examines non-genetic intra-tumor heterogeneity in lung tumors, finding it significantly influences phenotypic diversity and evolutionary dynamics beyond genetic factors.