Differential Mast Cell Outcomes Are Sensitive to FcϵRI-Syk Binding Kinetics
S. L. Schwartz, C. Cleyrat, M. Olah, P. Relich, G. Phillips, W. S. Hlavacek, K. A. Lidke, B. S. Wilson, D. Lidke
The paper uses single molecule imaging to study FcϵRI-Syk binding dynamics in mast cells, showing that altered binding kinetics affect signaling outcomes.
bioRxiv · Jun 9, 2017Cell Biology