Aedes aegypti Malpighian tubules are immunologically activated following systemic Toll activation
S. D. Sneed, S. B. Dwivedi, C. DiGate, S. Denecke, M. Povelones
This study shows that Aedes aegypti Malpighian tubules directly respond to systemic Toll activation by upregulating Toll pathway target genes and overlapping with hemolymph proteomic changes, suggesting a role in mosquito humoral immunity.
bioRxiv · Aug 21, 2022Immunology