eIF4A is stimulated by the pre-initiation complex and enhances recruitment of mRNAs regardless of structural complexity
P. Yourik, C. E. Aitken, F. Zhou, N. Gupta, A. G. Hinnebusch, J. R. Lorsch
This study shows eIF4A enhances mRNA recruitment by interacting with the PIC and modulating ribosomal subunit conformation, regardless of mRNA structural complexity.
bioRxiv · Aug 24, 2017Biophysics