Maternal Obesity and Western-style Diet Impair Fetal and Juvenile Offspring Skeletal Muscle Insulin-Stimulated Glucose Transport in Nonhuman Primates
W. Campodonico-Burnett, B. Hetrick, S. R. Wesolowski, S. Schenk, D. L. Takahashi, T. A. Dean, E. L. Sullivan, P. Kievit, M. Gannon, K. Aagaard-Tillery, J. E. Friedman, C. E. McCurdy
This study shows maternal obesity and western-style diet reduce fetal and juvenile offspring skeletal muscle insulin-stimulated glucose uptake in nonhuman primates, with effects persisting despite switching to a healthy diet.
bioRxiv · Dec 3, 2019Physiology