A Non-redundant Role for T cell-derived IL-22 in Antibacterial Defense of Colonic Crypts
C. T. Weaver, C. L. Zindl, S. J. Witte, V. A. Laufer, M. Gao, Z. Yue, D. J. Silberger, S. N. Harbour, J. R. Singer, D. Pham, C. E. Moseley, B. Cai, H. Turner, F. E. Lund, B. A. Vallance, , R. D. Hatton
This study shows that T cell-derived IL-22 is essential for antibacterial defense and damage control in intestinal crypts, despite ongoing ILC3-derived IL-22 production.
bioRxiv · May 11, 2021 · PreprintImmunology