Author

C. E. Wong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

L. C. Wheeler· 2 shared M. J. Harms· 2 shared A. J. Morrison· 1 shared A. Perkins· 1 shared J. A. Anderson· 1 shared

Activity by Year

2017-2020 · peak 1/yr

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5 top collaborators · 8 mutual co-author links

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2 shared papersBiophysics

L. C. Wheeler

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2 papers

Recent·Most cited

Learning Peptide Recognition Rules for a Low-Specificity Protein

L. C. Wheeler, A. Perkins, C. E. Wong, M. J. Harms

The paper trains a machine learning model to predict peptide binding specificity for a low-specificity protein by analyzing biochemical features rather than amino acid sequences, revealing hydrophobicity and shape complementarity as key factors.

bioRxiv · Jun 2, 2020Biophysics

Conservation of specificity in two low-specificity proteins

L. C. Wheeler, J. A. Anderson, A. J. Morrison, C. E. Wong, M. J. Harms

This study shows that low-specificity S100 proteins maintain conserved peptide binding specificity across species, indicating evolutionary constraints and subfunctionalization of paralogs.

bioRxiv · Oct 25, 2017Biochemistry