A. Perkins

Role of the antiparallel double-stranded filament form of FtsA in activating the Escherichia coli divisome

This paper investigates the role of FtsA's antiparallel double-stranded filament form in divisome activation in E. coli, showing it is required for septum synthesis but not divisome assembly.

Modeling cellular co-infection and reassortment of bluetongue virus in Culicoides midges

The paper develops mathematical models to study bluetongue virus reassortment in Culicoides midges, finding that small fitness differences between strains significantly affect reassortant frequency.

A bacterial inflammation sensor regulates c-di-GMP signaling, adhesion, and biofilm formation.

This paper identifies a bacterial sensor that detects HOCl, a host-derived oxidant, and links its activation to biofilm formation through a redox-sensitive zinc-cysteine switch.

Learning Peptide Recognition Rules for a Low-Specificity Protein

The paper trains a machine learning model to predict peptide binding specificity for a low-specificity protein by analyzing biochemical features rather than amino acid sequences, revealing hydrophobicity and shape complementarity as key factors.

Highly diverse fungal communities in carbon-rich aquifers of two contrasting lakes in Northeast Germany

This study examines fungal communities in groundwater near two lakes in NE Germany, finding high diversity and functional roles in degrading organic matter.

Helicobacter pylori Senses Bleach as a Chemoattractant Using a Cytosolic Chemoreceptor.

This study identifies that Helicobacter pylori uses a cytosolic chemoreceptor to sense bleach as a chemoattractant, aiding in colonization of inflamed gastric tissue.

Model-based analysis of experimental hut data elucidates multifaceted effects of a volatile chemical on Aedes aegypti mosquitoes

This paper develops a statistical framework to analyze experimental hut data and quantify the effects of transfluthrin on Aedes aegypti mosquito behaviors and knockdown rates at different dosages and distances.