CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis
S. M. Camus, M. D. Camus, C. Figueras-Novoa, G. Boncompain, L. A. Sadacca, C. Esk, A. Bigot, G. W. Gould, D. Kioumourtzoglou, F. Perez, N. J. Bryant, S. Mukherjee, F. M. Brodsky
The paper identifies CHC22 clathrin as mediating ERGIC-derived membrane traffic essential for GLUT4 sequestration in humans, distinct from mice lacking CHC22.
bioRxiv · Aug 12, 2019Cell Biology