Structural Insights into the ATP-dependent Activation of NOD-like Receptor with Pyrin 3 (NLRP3) Protein by Molecular Dynamics Simulation
C. F. Sandall, J. A. MacDonald
This study uses molecular dynamics simulations to show that ATP binding induces conformational changes in NLRP3, while ADP binding stabilizes its structure.
bioRxiv · May 3, 2023Biochemistry