Author

C. G. Callan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:CITE-seq· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Research Focus:clustering· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

T. Mora· 2 shared Y. Elhanati· 2 shared Z. Sethna· 2 shared A. Levine· 1 shared A. M. Walczak· 1 shared A. Mayer· 1 shared A. Walczak· 1 shared C. S. Dudgeon· 1 shared

Activity by Year

2016-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

T. Mora

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Author profile →

3 papers

Recent·Most cited

Measures of epitope binding degeneracy from T cell receptor repertoires

A. Mayer, C. G. Callan

The paper quantifies epitope binding degeneracy in T cell receptors using sequence near-coincidences and shows how paired-chain coincidences reveal antigen-driven selection.

bioRxiv · Jul 25, 2022 · PreprintImmunology

Predicting the spectrum of TCR repertoire sharing with a data-driven model of recombination

Y. Elhanati, Z. Sethna, C. G. Callan, T. Mora, A. M. Walczak

The paper develops a model to predict TCR repertoire sharing by accounting for recombination biases and thymic selection, introducing a classifier that performs well across cohort sizes.

bioRxiv · Mar 2, 2018Immunology

Mouse T cell repertoires as statistical ensembles: overall characterization and age dependence

Z. Sethna, Y. Elhanati, C. S. Dudgeon, C. G. Callan, A. Levine, T. Mora, A. Walczak

The paper analyzes T cell repertoires in mice to show age-related increases in VDJ recombination diversity and similar selection effects in thymus and blood.

bioRxiv · Nov 10, 2016Immunology