Author

C. G. James

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Evolutionary Biology· 1

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

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L. Sandell· 1 shared N. P. Sharp· 1 shared S. P. Otto· 1 shared

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2018-2018 · peak 1/yr

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1 shared paperEvolutionary Biology

L. Sandell

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1 paper

Recent·Most cited

The genome-wide rate and spectrum of spontaneous mutations differs between haploid and diploid yeast

N. P. Sharp, L. Sandell, C. G. James, S. P. Otto

This study compares mutation rates and spectra between haploid and diploid yeast, finding haploids have more single-nucleotide and mitochondrial mutations, while diploids have more structural changes and detrimental mutations.

bioRxiv · Jan 19, 2018Evolutionary Biology