Activation of p21 limits acute lung injury and induces early senescence after acid aspiration and mechanical ventilation
J. Blazquez-Prieto, C. Huidobro, I. Lopez-Alonso, L. Amado-Rodriguez, P. Martin-Vicente, C. Lopez-Martinez, I. Crespo, C. Pantoja, P. J. Fernandez-Marcos, M. Serrano, J. I. Sznajder, G. M. Albaiceta
This study shows that activation of the p53/p21 pathway limits acute lung injury by reducing cell apoptosis but also induces early senescence in alveolar cells.
Translational Research · Jul 1, 2021Peer-reviewedCell Biology