C. Igler

Prophage maintenance is determined by environment-dependent selective sweeps rather than mutational availability

The paper shows that prophage maintenance in bacteria is driven by environmental selective sweeps rather than mutation rates or accessory gene cooperation.

Assessing the importance of resistance, persistence and hyper-mutation for antibiotic treatment success with stochastic modelling

This study uses stochastic modelling to show that antibiotic treatment failure can result from resistance, persistence, or hyper-mutation, with distinct dependencies on antibiotic concentration and timing.

Plasmid co-infection: linking biological mechanisms to ecological and evolutionary dynamics

This paper reviews how biological processes of plasmid co-infection are modeled and analyzes their impact on eco-evolutionary outcomes, showing frequency-dependent selection from beneficial and detrimental effects.

Conjugative plasmid transfer is limited by prophages but can be overcome by high conjugation rates

The paper shows prophages limit plasmid transfer but high conjugation rates can overcome this limitation in E. coli.

Multi-step vs. single-step resistance evolution under different drugs, pharmacokinetics and treatment regimens

The paper investigates how drug resistance evolves through single or multiple mutations and shows that treatment strategies affect resistance development and population diversity.