B. Siedentop

Assessing the role of bacterial innate and adaptive immunity as barriers to conjugative plasmids

This study models how bacterial innate and adaptive immunity affect plasmid spread, finding that immunity suppresses costly plasmids but not beneficial ones.

My host's enemy is my enemy: plasmids carrying CRISPR-Cas as a defence against phages

The paper develops a stochastic model to evaluate CRISPR-Cas plasmid-based anti-phage protection, showing it is robust except under specific parameter conditions where segregation loss enables phage outbreaks.

Plasmid co-infection: linking biological mechanisms to ecological and evolutionary dynamics

This paper reviews how biological processes of plasmid co-infection are modeled and analyzes their impact on eco-evolutionary outcomes, showing frequency-dependent selection from beneficial and detrimental effects.