Author

C. J. Harrison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. C. Cuming· 1 shared A. Elder· 1 shared A. Komkov· 1 shared A. Penik· 1 shared A. Ptasinska· 1 shared A. Smith· 1 shared A. Stewart· 1 shared C. A. Cargo· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPlant Biology

A. C. Cuming

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3 papers

Recent·Most cited

Diverse branching forms regulated by a core auxin transport mechanism in plants

V. Spencer, L. Bentall, C. J. Harrison

The paper identifies PIN-mediated auxin transport as the ancestral mechanism for branching in vascular plants, showing its role in both branch initiation and plastic outgrowth in lycophytes.

bioRxiv · Sep 15, 2022 · PreprintPlant Biology

Epigenetic regulator genes direct lineage switching in MLL-AF4 leukaemia

R. Tirtakusuma, K. Szoltysek, P. Milne, V. V. Grinev, A. Ptasinska, C. Meyer, S. Nakjang, J. Y. Hehir-Kwa, D. Williamson, P. Cauchy, S. A. Assi, M. R. Imperato, F. Vogiatzi, S. Lin, M. Wunderlich, , M. J Thirman

This study shows that lineage switching in MLL-AF4 leukaemia is driven by dysregulation of epigenetic regulators like NuRD, leading to reprogramming of gene regulatory networks from B lymphoid to myeloid.

bioRxiv · Jul 16, 2021Cancer Biology

PpRPK2 modulates auxin homeostasis and transport to specify stem cell identity and plant shape in the moss Physcomitrella

Z. Nemec Venza, C. Madden, A. Stewart, W. Liu, O. Novak, A. Penik, A. C. Cuming, Y. Kamisugi, C. J. Harrison

This study shows that the moss CLAVATA pathway modulates auxin homeostasis and transport to control stem cell identity and plant shape, suggesting this mechanism is conserved in land plants.

bioRxiv · Jun 24, 2021 · PreprintPlant Biology