A FASII inhibitor prevents staphylococcal evasion of daptomycin by inhibiting phospholipid decoy production
C. J. Pee, V. Pader, E. V. Ledger, A. Edwards
This study shows that an FASII inhibitor enhances daptomycin's effectiveness against S. aureus by blocking phospholipid decoy production, which inactivates the antibiotic.
bioRxiv · Sep 27, 2018Microbiology