Author

C. Kegler

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Hacker· 1 shared H. B. Bode· 1 shared J. Woehnert· 1 shared K. Weickhmann· 1 shared L. Zhao· 1 shared X. Cai· 1 shared

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2018-2018 · peak 1/yr

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1 shared paperBiochemistry

C. Hacker

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1 paper

Recent·Most cited

Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS

C. Hacker, X. Cai, C. Kegler, L. Zhao, K. Weickhmann, H. B. Bode, J. Woehnert

The paper identifies structural and thermodynamic rules governing docking domain interactions in NRPSs, enabling predictable changes in peptide product spectra through residue exchange.

bioRxiv · Jun 18, 2018Biochemistry