Author

C. Kueng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

M. Nash· 2 shared R. Vanella· 2 shared A. A. Schoepfer· 1 shared J. Ren· 1 shared O. Protsenko· 1 shared V. Doffini· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersBioengineering

M. Nash

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2 papers

Recent·Most cited

Deep Mutational Scanning Reveals a De Novo Disulfide Bond and Combinatorial Mutations for Engineering Thermostable Myoglobin

C. Kueng, O. Protsenko, R. Vanella, M. Nash

This study uses deep mutational scanning to identify mutations that enhance thermostability in human myoglobin, discovering a de novo disulfide bond and combinatorial mutations that significantly increase stability.

bioRxiv · Feb 24, 2024Bioengineering

Understanding Activity-Stability Tradeoffs in Biocatalysts by Enzyme Proximity Sequencing

R. Vanella, C. Kueng, A. A. Schoepfer, V. Doffini, J. Ren, M. Nash

The paper introduces EP-Seq, a method to simultaneously measure enzyme stability and activity across thousands of mutations, and applies it to D-amino acid oxidase to identify activity-stability tradeoffs.

bioRxiv · Feb 24, 2023Bioengineering