Author

C. L. Brand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Organism:Drosophila· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Approach:Bayesian inference· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1

Frequent Co-Authors

M. T. Levine· 2 shared E. P. Nielsen· 1 shared G. T. Oliver· 1 shared I. Z. Farkas· 1 shared S. Andersen· 1 shared S. Ditlevsen· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 6 mutual co-author links

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2 shared papersEvolutionary Biology

M. T. Levine

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3 papers

Recent·Most cited

Recurrent duplication and diversification of a vital DNA repair gene family across Drosophila

C. L. Brand, G. T. Oliver, I. Z. Farkas, M. T. Levine

This study investigates the evolutionary diversification of the Spartan gene family in Drosophila, finding recurrent duplication, divergence, and positive selection linked to DNA satellite dynamics.

bioRxiv · Oct 4, 2023Evolutionary Biology

Applying Historical Data in a Nonlinear Mixed-Effects Model Can Reduce the Number of Control Rats Required for Calculation of the Relative Potency of Insulin Analogues

E. P. Nielsen, S. Andersen, C. L. Brand, S. Ditlevsen

This paper shows that using historical data in a nonlinear mixed-effects model reduces the number of control rats needed for insulin analogue potency studies by 23-51%.

bioRxiv · Sep 10, 2021Pharmacology & Toxicology

Cross-species incompatibility between a DNA satellite and the Drosophila Spartan homolog poisons germline genome integrity

C. L. Brand, M. T. Levine

This study shows that a species-specific DNA satellite and a chromosomal protein from a related species incompatibly disrupt germline genome integrity when combined.

bioRxiv · Aug 13, 2021Evolutionary Biology