Activation of Histone 3 Lysine 9 methyl writing and reading capabilities within the G9a-GLP heterodimer
N. A. Sanchez, L. M. Kallweit, C. L. Clemmer, M. J. Trnka, B. Al-Sady
This study shows that the G9a-GLP heterodimer enhances H3K9 methylation reading and writing compared to homodimers, with increased turnover and recognition of H3K9me2.
bioRxiv · May 5, 2021Biochemistry