Author

C. L. Willis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. M. Bailey· 1 shared C. R. Back· 1 shared C. R. Pudney· 1 shared F. Alberti· 1 shared G. D. Foster· 1 shared J. A. Davies· 1 shared J. Alnawah· 1 shared J. E. M. Stach· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

A. M. Bailey

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2 papers

Recent·Most cited

Delineation of the Complete Reaction Cycle of a Natural Diels-Alderase

L. Maschio, C. R. Back, J. Alnawah, J. I. Bowen, S. T. Johns, S. Z. Mbatha, L.-C. Han, N. R. Lees, K. Zorn, J. E. M. Stach, M. A. Hayes, M. W. van der Kamp, C. R. Pudney, S. G. Burston, C. L. Willis, P. R. Race

This study provides a molecular description of the complete reaction cycle of the natural Diels-Alderase AbyU using X-ray crystallography, kinetics, and computational simulations.

bioRxiv · Apr 18, 2024Biochemistry

Biosynthesis of pleuromutilin congeners using an Aspergillus oryzae expression platform

F. Alberti, K. Khairudin, J. A. Davies, S. Sangmalee, C. L. Willis, G. D. Foster, A. M. Bailey

This study identifies two shunt pathways in pleuromutilin biosynthesis using Aspergillus oryzae, leading to three novel congeners with varied antimicrobial activity.

bioRxiv · Dec 3, 2022 · PreprintMicrobiology