Mammalian cells-based platforms for the generation of SARS-CoV-2 virus-like particles
G. Elfayres, R. R. Paswan, L. Sika, M.-P. Girard, S. Khalfi, C. Letanneur, K. Milette, A. Singh, G. Kobinger, L. Berthoux
This paper develops a platform for generating SARS-CoV-2 virus-like particles (VLPs) using mammalian cells, showing that co-expression of four structural proteins enables efficient VLP production and stable cell lines for vaccine development.
bioRxiv · Jul 24, 2023Microbiology