Reconstitution of a minimal ESX-5 type VII secretion system suggests a role for PPE proteins in outer membrane transport of proteins
C. M. Bunduc, Y. Ding, C. Kuijl, T. C. Marlovits, W. Bitter, E. N. G. Houben
The paper reconstitutes the ESX-5 T7SS in Mycobacterium smegmatis to show that PPE proteins localize to the outer membrane and are required for active secretion.
bioRxiv · Sep 5, 2022Microbiology