Ilaprazole and other novel prazole-based compounds that bind Tsg101 inhibit viral budding of HSV-1/2 and HIV from cells
J. Leis, C.-H. Luan, J. E. Audia, S. F. Dunne, C. M. Heath
This paper shows prazole drugs like ilaprazole block HSV-1/2 and HIV-1 release by inhibiting Tsg101 interaction, with ilaprazole being more potent than tenatoprazole.
bioRxiv · May 4, 2020Microbiology