Structural modification of naturally-occurring phenolics as a strategy for developing cytotoxic molecules towards cancer cells
P. A. Olim, R. B. Pereira, M. J. G. Fernandes, C. M. Natal, J. R. A. Coelho, A. G. Fortes, M. S. T. Goncalves, D. M. Pereira
This study synthesizes and tests semisynthetic derivatives of natural phenolics for cytotoxicity against cancer cells, finding two 6-hydroxyflavanone derivatives to be highly cytotoxic with selective activity against cancer cells.
Archiv der Pharmazie · Oct 11, 2023Peer-reviewedPharmacology & Toxicology