Author

C. M. Santi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Assay:electrophysiology· 1 Assay:flow cytometry· 1

Frequent Co-Authors

J. J. Ferreira· 2 shared A. Cassina· 1 shared A. Darszon· 1 shared A. G. Novero· 1 shared C. Amazu· 1 shared C. L. Trevino· 1 shared C. Ritagliati· 1 shared C. Stival· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCell Biology

J. J. Ferreira

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Author profile →

3 papers

Recent·Most cited

The sodium-proton exchangers sNHE and NHE1 control plasma membrane hyperpolarization in mouse sperm.

A. G. Novero, P. T. Rodriguez, J. L. de la Vega Beltran, L. J. Schiavi-Ehrenhaus, G. M. Luque, M. Carruba, C. Stival, I. Gentile, C. Ritagliati, C. M. Santi, T. Nishigaki, D. Krapf, M. G. Buffone, A. Darszon, C. L. Trevino, D. Krapf

This study identifies Na+/H+ exchangers as key regulators of plasma membrane hyperpolarization in mouse sperm, challenging the role of PKA and revealing a novel pathway involving cAMP, calcium, and SLO3 K+ channels.

bioRxiv · Mar 4, 2024Cell Biology

Increased mitochondrial activity upon CatSper channel activation is required for sperm capacitation.

J. J. Ferreira, A. Cassina, P. Irigoyen, M. Ford, S. Pietroroia, R. Radi, C. M. Santi, R. Sapiro

The paper shows mitochondrial respiration and calcium influx via CatSper are required for sperm hyperactivation and fertilization.

bioRxiv · May 4, 2021Cell Biology

A novel sodium signaling complex regulates uterine activity

J. J. Ferreira, C. Amazu, L. C. Puga-Molina, X. Ma, S. K. England, C. M. Santi

This paper identifies a novel sodium signaling complex involving NALCN and SLO2.1 channels that regulates uterine smooth muscle cell membrane potential and contractility.

bioRxiv · Jul 31, 2020 · PreprintCell Biology