Optimization of the TeraTox assay for preclinical teratogenicity assessment
M. Jaklin, J. D. Zhang, N. Schaefer, N. Clemann, P. Barrow, E. Kueng, L. Sach-Peltason, C. McGinnis, M. Leist, S. Kustermann
The paper optimizes the TeraTox assay for teratogenicity prediction using human stem cells and machine learning, achieving 69% accuracy and better sensitivity than existing methods.
bioRxiv · Jul 6, 2021Pharmacology & Toxicology