Author

S. Kustermann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

K. Achberger· 2 shared L. Mesch· 2 shared M. Cipriano· 2 shared M. Jaklin· 2 shared M. Mesquida· 2 shared P. Loskill· 2 shared S. Liebau· 2 shared A. Kleger· 1 shared

Activity by Year

2021-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersCell Biology

K. Achberger

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Aged human iPSC-RPE organoid cultures display hallmarks of drusen formation

L. Mesch, N. Pashkovskaia, V. Cora, S. Pars, S. Corti, M. Cipriano, P. Loskill, E. Koertvely, S. Kustermann, M. Mesquida, A. Kleger, S. Liebau, K. Achberger

This study develops an in vitro model of aged human iPSC-derived RPE organoids that display AMD-like features including drusen formation and age-related alterations.

bioRxiv · Oct 12, 2021 · PreprintCell Biology

Optimization of the TeraTox assay for preclinical teratogenicity assessment

M. Jaklin, J. D. Zhang, N. Schaefer, N. Clemann, P. Barrow, E. Kueng, L. Sach-Peltason, C. McGinnis, M. Leist, S. Kustermann

The paper optimizes the TeraTox assay for teratogenicity prediction using human stem cells and machine learning, achieving 69% accuracy and better sensitivity than existing methods.

bioRxiv · Jul 6, 2021Pharmacology & Toxicology

Human immunocompetent Choroid-on-Chip: a novel tool for studying ocular effects of biological drugs

M. Cipriano, K. Schluender, C. Probst, K. Linke, M. Weiss, M. J. Fischer, L. Mesch, K. Achberger, S. Liebau, M. Mesquida, V. Nicolini, A. Schneider, A. M. Giusti, S. Kustermann, P. Loskill

The paper develops a human immunocompetent Choroid-on-Chip model to study ocular effects of biological drugs and assess immunotoxicity.

bioRxiv · May 12, 2021Bioengineering

In vitro teratogenicity testing using a 3D, embryo-like gastruloid system

V. Mantziou, P. Baillie-Benson, M. Jaklin, S. Kustermann, A. Martinez Arias, N. Moris

This study uses a 3D gastruloid model to assess teratogenicity of seven reference compounds in mouse and human systems, showing morphological and gene expression changes indicative of developmental defects.

bioRxiv · Mar 30, 2021Pharmacology & Toxicology