Casein kinase II promotes piRNA production through direct phosphorylation of USTC component TOFU-4
C. Mello, G. ZHANG, C. Zheng, y.-h. ding
This study identifies casein kinase II (CK2) as a regulator of piRNA production by phosphorylating TOFU-4, a component of the USTC complex, and shows its role in aging-related piRNA silencing defects.
bioRxiv · Aug 9, 2023Cell Biology