Novel loading protocol combines highly efficient encapsulation of exogenous therapeutic toxin with preservation of extracellular vesicles properties, uptake and cargo activity
S. Zuppone, N. Zarovni, K. Noguchi, F. Loria, C. Morasso, A. Lohmus, I. Nakase, R. Vago
The paper introduces a novel pH-based method for loading therapeutic toxins into extracellular vesicles, preserving their properties and enhancing cargo activity.
bioRxiv · Nov 12, 2023Cancer Biology