C. N. Reddy

Dissociation of CED-4 from CED-9 upon EGL-1 binding: Molecular mechanism of linear apoptotic pathway in Caenorhabditis elegans

This study models the CED-9/CED-4/EGL-1 ternary complex and simulates its dynamics to elucidate the molecular mechanism of CED-4 release from CED-9 during apoptosis in C. elegans.

Designing BH3-mimetic Peptide Inhibitors for the Viral Bcl-2 Homologs A179L and BHRF1: Importance of long-range electrostatic interactions

This study designs BH3-mimetic peptides to inhibit viral Bcl-2 homologs A179L and BHRF1, finding that long-range electrostatic interactions are critical for inhibitor efficacy.