Promyelocytic Leukemia Protein regulates Angiogenesis and Epithelial-Mesenchymal Transition to limit metastasis in MDA-MB-231 breast cancer cells.
A. P. Vogiatzoglou, S. Spanou, N. Sachini, E. Drakos, C. Nikolaou, T. Makatounakis, A. Kretsovali, J. Papamatheakis
This study shows that PML suppresses breast cancer metastasis by inhibiting angiogenesis and EMT through interactions with HIF1a and TWIST2.
bioRxiv · Aug 28, 2022Cancer Biology