Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization
W. Zhang, C. Kim, C. P. Tam, V. Lelyveld, S. Bala, J. Chaput, J. W. Szostak
This study investigates the effects of threo-nucleotides on nonenzymatic template-directed polymerization, finding that they are less efficient than ribo-nucleotides in primer extension.
bioRxiv · Nov 17, 2020Biochemistry