Methylation-directed Acetylation of Histone H3 Regulates Developmental Sensitivity to Histone Deacetylase Inhibition
L.-Y. Huang, D.-W. Hsu, C. Pears
This study shows that acetylation of H3K4me3 histones, regulated by Sgf29's TTD, determines developmental sensitivity to TSA, with implications for drug response biomarkers.
bioRxiv · Jul 22, 2020Pharmacology & Toxicology