Author

L.-Y. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

A.-L. Huang· 1 shared B.-Y. Li· 1 shared C. Liang· 1 shared C. Pears· 1 shared C. Xu· 1 shared C. Yi· 1 shared C. Zheng· 1 shared C.-J. Gu· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperMicrobiology

A.-L. Huang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identification of bis-benzylisoquinoline alkaloids as SARS-CoV-2 entry inhibitors from a library of natural products in vitro

C.-L. He, L.-Y. Huang, K. Wang, C.-J. Gu, J. Hu, G.-J. Zhang, W. Xu, Y.-H. Xie, N. Tang, A.-L. Huang

This study identifies bis-benzylisoquinoline alkaloids as SARS-CoV-2 entry inhibitors through in vitro screening of natural products.

bioRxiv · Dec 13, 2020Microbiology

Methylation-directed Acetylation of Histone H3 Regulates Developmental Sensitivity to Histone Deacetylase Inhibition

L.-Y. Huang, D.-W. Hsu, C. Pears

This study shows that acetylation of H3K4me3 histones, regulated by Sgf29's TTD, determines developmental sensitivity to TSA, with implications for drug response biomarkers.

bioRxiv · Jul 22, 2020Pharmacology & Toxicology

Accurate Diagnosis of Colorectal Cancer Based on Histopathology Images Using Artificial Intelligence

K.-S. Wang, G. Yu, C. Xu, X.-H. Meng, J. Zhou, C. Zheng, Z. Deng, L. Shang, R. Liu, S. Su, X. Zhou, Q. Li, J. Li, J. Wang, K. Ma, , H.-W. Deng

This paper develops an AI tool for colorectal cancer diagnosis using histopathology images, achieving high accuracy and consistency across multiple centers.

bioRxiv · Mar 15, 2020Pathology