DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7
L. De Jesus Kim, L. J. Friedman, C. Ramsoomair, J. Gelles, S. P. Bell
The paper shows DDK controls Cdc45-GINS binding multiplicity to Mcm2-7, affecting CMG formation and replication initiation.
bioRxiv · Dec 9, 2020Cell Biology