Synthetic Genome Shuffling of Poxviruses through Yeast for Next-Generation Oncolytic Platforms
Aimeric Agaoua, C. Rey, Julie Hortelano, A-I Moro, Benoît Grellier, Philippe Erbs
The paper describes a method using yeast-based genome shuffling to generate chimeric poxviruses with enhanced oncolytic activity and immune stimulation.
bioRxiv · Mar 6, 2026 · PreprintSynthetic Biology