From Cardiac Myosin to the Beta Receptor: Autoantibodies Promote a Fibrotic Transcriptome and Reduced Ventricular Recovery in Human Myocarditis
J. Myers, C. Sandel, K. Alvarez, L. Garman, G. wiley, C. Montgomery, P. Gaffney, S. Stavrakis, D. Fairweather, K. Bruno, Y. D. Zhao, L. T. Cooper, M. W. Cunningham
This study identifies cardiac myosin autoantibodies associated with reduced ejection fraction and fibrotic transcriptomes in nonrecovered myocarditis patients.
bioRxiv · Jun 19, 2024 · PreprintImmunology