Author

K. Alvarez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

B. Canard· 2 shared F. Ferron· 2 shared M. Feracci· 2 shared A. Chazot· 1 shared A. Moussa· 1 shared C. Montgomery· 1 shared C. Sandel· 1 shared C. T. De Jesus· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

B. Canard

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

From Cardiac Myosin to the Beta Receptor: Autoantibodies Promote a Fibrotic Transcriptome and Reduced Ventricular Recovery in Human Myocarditis

J. Myers, C. Sandel, K. Alvarez, L. Garman, G. wiley, C. Montgomery, P. Gaffney, S. Stavrakis, D. Fairweather, K. Bruno, Y. D. Zhao, L. T. Cooper, M. W. Cunningham

This study identifies cardiac myosin autoantibodies associated with reduced ejection fraction and fibrotic transcriptomes in nonrecovered myocarditis patients.

bioRxiv · Jun 19, 2024 · PreprintImmunology

The activation chain of the broad-spectrum antiviral bemnifosbuvir at atomic resolution

A. Chazot, C. Zimberger, M. Feracci, A. Moussa, S. Good, J.-P. Sommadossi, K. ALVAREZ, F. Ferron, B. Canard

This paper reveals the activation pathway of bemnifosbuvir to its active form AT-9010, showing the required enzymes and structural insights into the process.

bioRxiv · Feb 16, 2024 · PreprintBiochemistry

A high-throughput fluorescence polarization assay to discover inhibitors of arenavirus and coronavirus exoribonucleases

S. G. Hernandez Tapia, M. Feracci, C. T. De Jesus, P. El-Kazzi, R. Kaci, L. Garlatti, E. Decroly, B. Canard, F. Ferron, K. Alvarez

This paper develops a high-throughput fluorescence polarization assay to screen inhibitors of exoribonucleases from arenaviruses and coronaviruses and validates it with a small compound library.

bioRxiv · Apr 2, 2021 · PreprintBiochemistry