NRF1 Association with AUTS2-Polycomb Mediates Specific Gene Activation in the Brain
S. Liu, K. A. Aldinger, C. V. Cheng, T. Kiyama, M. Dave, H. K. McNamara, S. G. Caraffi, I. Ivanovski, E. Errichiello, C. Zweier, O. Zuffardi, M. Schneider, A. S. Papavasiliou, M. S. Perry, M. T. Cho, , D. Reinberg
The paper identifies NRF1's role in PRC1.3 recruitment to chromatin and shows AUTS2 mutations disrupt gene regulation and motor neuron differentiation.
bioRxiv · Mar 30, 2021Biochemistry