Development of autotrophy in Escherichia coli through adaptive laboratory evolution
Shao‐Yu Huang, Jian-Hau Peng, Shou-Chen Lo, Chia-Ho Liu, Yi‐Cheng Lin, En‐Pei Isabel Chiang, C. W. Huang
This study achieves autotrophy in E. coli through adaptive laboratory evolution, identifying mutations and gene expression changes that enable CO2 fixation.
bioRxiv · Feb 25, 2026 · PreprintMicrobiology